Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
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- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
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- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $238.00 | Total: $1,190.00 |
| 1 | 10 | $201.60 | Total: $2,016.00 |
| 1 | 25 | $170.80 | Total: $4,270.00 |
| 1 | 50 | $145.60 | Total: $7,280.00 |
| 1 | 100 | $126.00 | Total: $12,600.01 |
Overview
JTK-109 is an inhibitor of hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor and inhibits G1b and G3a subgenomic replicons and recombinant enzymes.
Chemical Properties
| Molecular Formula | C37H33ClFN3O4 |
| Molecular Weight | 638.13 |
| CAS Numbers | 480462-62-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | FC1=C(C=2N(C=3C(N2)=CC(C(O)=O)=CC3)C4CCCCC4)C=CC(OCC5=C(C=CC(=C5)N6C(=O)CCC6)C7=CC=C(Cl)C=C7)=C1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Hirashima S, et al. Benzimidazole derivatives bearing substituted biphenyls as hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors structure-activity relationship studies and identification of a potent and highly selective inhibitor JTK-109. J Med Chem. 2006 Jul 27;49[15] 4721-36.