Enzyme Inhibitors

PXS-6302 hydrochloride View larger

PXS-6302 hydrochloride

AT60438L

CAS 2584947-79-3

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$194.00

$194.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $87.30 Total: $8,730.00
150 $100.88 Total: $5,044.00
125 $118.34 Total: $2,958.50
110 $139.68 Total: $1,396.80
15 $164.90 Total: $824.50

Data sheet

Molecular FormulaC10H11ClF3NO2S
Molecular Weight301.71
CAS Numbers2584947-79-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeS(C(C(=CCN)F)(F)F)(=O)(=O)C1=CC=CC=C1.Cl
ReferencesChaudhari N, et al. Topical application of an irreversible small molecule inhibitor of lysyl oxidases ameliorates skin scarring and fibrosis. Nat Commun. 2022 Sep 22;13[1] 5555.

More info

PXS-6302 hydrochloride is a potent irreversible lysine oxidase (LOX) inhibitor, inhibiting Bovine LOX, rh LOXL1, rh LOXL2, rh LOXL3, and rh LOXL4 with IC50 of 3.7 ?M, 3.4 ?M, 0.4 ?M, 1.5 ?M, and 0.3 ?M, respectively. PXS-6302 hydrochloride penetrates easily through the skin and is able to reduce collagen accumulation, significantly improving the appearance of scars.