Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $204.00 | Total: $1,020.00 |
| 1 | 10 | $172.80 | Total: $1,728.00 |
| 1 | 25 | $146.40 | Total: $3,660.00 |
| 1 | 50 | $124.80 | Total: $6,240.00 |
| 1 | 100 | $108.00 | Total: $10,800.00 |
Overview
AVE5688, an inhibitor of glycogen phosphorylase (GP), has IC50 values of 430 nM and 915 nM, and Kd values of 170 nM and 530 nM for rmGPb and rmGPa, respectively. It is suitable for research on type 2 diabetes.
Chemical Properties
| Molecular Formula | C16H8ClF5N2O5 |
| Molecular Weight | 438.69 |
| CAS Numbers | 613260-13-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O(C(F)(F)F)C1=C(NC(NC(=O)C2=C(Cl)C=C(F)C(F)=C2)=O)C=CC(C(O)=O)=C1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Anderka O, et al. Thermodynamic characterization of allosteric glycogen phosphorylase inhibitors. Biochemistry. 2008 Apr 22;47[16] 4683-91.