Enzyme Inhibitors

NSC-658497 View larger

NSC-658497

AOB6653

CAS No: 909197-38-2

 

Chemical Name: (3Z)-3-[[(5Z)-5-[(4-Nitrophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]methylidene]chromene-2,4-dione

 

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Molarity Calculation Cart®

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$590.00

$590.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $265.50 Total: $26,550.00
150 $306.80 Total: $15,340.00
125 $359.90 Total: $8,997.50
110 $424.80 Total: $4,248.00
15 $501.50 Total: $2,507.50

Data sheet

Molecular FormulaC20H10N2O6S2
Molecular Weight438.43
CAS Numbers909197-38-2
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC

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Novel inhibitor of SOS1-Ras interaction, dose-dependently inhibiting SOS1 GEF activity

Reference:

Evelyn, CR., Duan, X., Biesiada, J., Seibel, WL., Meller, J., Zheng, Y., Rational Design of Small-Molecule Inhibitors Targeting the Ras GEF, SOS1, Chem. Biol., 2014, 21(12): 1618-28

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