Enzyme Inhibitors

Sepin-1 View larger

Sepin-1

AOB8333

CAS No: 163126-81-6

Chemical Name: 2,2-Dimethyl-5-nitro-2H-benzimidazole-1,3-dioxide

AOBIOUS launched this product in 2018

CITATIONS - Publications That Use AOBIOUS Product

1) Cancer Sci. 2021 Sep; 112(9): 3871–3883

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Molarity Calculation Cart®

HOW TO ORDER

$21.00

$21.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $9.45 Total: $945.00
150 $10.92 Total: $546.00
125 $12.81 Total: $320.25
110 $15.12 Total: $151.20
15 $17.85 Total: $89.25

Data sheet

Molecular FormulaC9H9N3O4
Molecular Weight223.19
CAS Numbers163126-81-6
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
InChl KeyYLVSVJDCTDBERH-UHFFFAOYSA-N
References1) PubMed PMID: 27530289. 2) PubMed PMID: 24525869.

More info

Novel noncompetitive inhibitor of separase

REFERENCES

1) Do HT, etc. Synthesis and activity of benzimidazole-1,3-dioxide inhibitors of separase. Bioorg Med Chem Lett. 26(18):4446-50. (2016) 

2) Zhang N, etc. Identification and Characterization of Separase Inhibitors (Sepins) for Cancer Therapy. J Biomol Screen. 19(6):878-89 (2014). 

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