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9-ING-41 (Elraglusib)

Cat No: AOB33534

Condition

CAS No: 1034895-42-5

Chemical Name: 3-(5-Fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione

AOBIOUS launched this product in 2018

CITATIONS - Publications That Use AOBIOUS Product

1) Biochem Biophys Res Commun. 2022 May 21; 605: 171–176.

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Quantity Discount Table - Order More To Get More Price Discount

Quantity	mg	Unit Price ($/mg or $/Unit)	Final Price
1	5	$21.25	Total: $106.25
1	10	$18.00	Total: $180.00
1	25	$15.25	Total: $381.25
1	50	$13.00	Total: $650.00
1	100	$11.25	Total: $1,125.00

Data sheet

Molecular Formula	C22H13FN2O5
Molecular Weight	404.35
CAS Numbers	1034895-42-5
Storage Condition	0°C (short term), -20°C (long term), desiccated
Solubility	DMSO
Purity	98% by HPLC
Synonym	9-ING-41; 9 ING 41; 9ING41; Elraglusib
IUPAC/Chemical Name	3-(5-fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)-1H-pyrrole-2,5-dione
InChl Key	FARXPFGGGGLENU-UHFFFAOYSA-N
InChl Code	InChI=1S/C22H13FN2O5/c1-25-7-13(11-5-17-18(6-15(11)25)30-9-29-17)19-20(22(27)24-21(19)26)14-8-28-16-3-2-10(23)4-12(14)16/h2-8H,9H2,1H3,(H,24,26,27)
SMILES Code	CN(C1=C2C=C3C(OCO3)=C1)C=C2C4=C(C5=COC6=C5C=C(F)C=C6)C(NC4=O)=O
References	1) Karmali R, et. GSK-3β inhibitor, 9-ING-41, reduces cell viability and halts proliferation of B-cell lymphoma cell lines as a single agent and in combination with novel agents. Oncotarget. 2017 Nov 11;8(70):114924-114934. 2) Ugolkov A, et. Combination Treatment with the GSK-3 Inhibitor 9-ING-41 and CCNU Cures Orthotopic Chemoresistant Glioblastoma in Patient-Derived Xenograft Models. Transl Oncol. 2017 Aug;10(4):669-678. 3) Pal K, Cao Y, Gaisina IN, Bhattacharya S, Dutta SK, Wang E, Gunosewoyo H, Kozikowski AP, Billadeau DD, Mukhopadhyay D. Inhibition of GSK-3 induces differentiation and impaired glucose metabolism in renal cancer. Mol Cancer Ther. 2014 Feb;13(2):285-96.