Enzyme Inhibitors

Protein Control Ligand
Pathway Inhibitors
- Enzyme Inhibitors
- Protein Inhibitors
- Transporter Inhibitors
  - ATPases
- Cell Inhibition
- Synthase
- Receptor Tyrosine Phosphatases (RTP)
- AChE
- Peptidase
- Autophagy
- Toll-Like Receptor (TLR)
Function Modulators
- Potentiators
- Allosteric
- Votage-Gated Ion Channel Blockers
- Major Facilitator Superfamily (MFS) Transporters
- Ligand-Gated Ion Channels
- Aquaporins
- Chlorine Channels
- Connexins and Pannexins
- KCC2 - K-Cl co-transporter
- ADC cytotoxin
- ADC Linker
- CFTR
- CCK
- Monoamine Transporter
- Proton pump
Activators
- Receptor Activators
- Inducer
- Openers
- Potassium Channel
G Protein-Coupled Receptor Ligands
- 5HT Receptors
- Adrenoceptor
- Angiotensin Receptor
- Cannabinoid Receptors
- CCK Receptors
- DA Receptors
- EAA Receptors
- Ghrelin Receptors
- GABA Receptors
- Histamine Receptors
- Leukotriene Receptors
- Metabotropic Glutamate Receptors
- Motilin Receptors
- Muscarinic Receptor
- Neuropeptide Receptors
- Opioid Receptors
- Orexin Receptors
- Orphan Receptors
- Prostanoid Receptors
- Proteinase-Activated Receptors
- Purinergic Receptors
- Ryanodine receptor
- Sigma Receptors
- Thrombin Receptor
- Vaniloid Receptor
- VIP and PACAP Receptors
- Neurotensin Receptors
- Urotensin Receptor
- Imidazoline receptor
- SMO Receptors
- Apelin Receptor
- β-arrestin/β2-adaptin
- KDM4
- Glucocorticoid Receptor
- Laminin Receptor
- AHR
- Amylin Receptor
- Bombesin Receptor
- Bradykinin Receptor
- CFTR
- CGRP Receptor
- CRFR
- Endothelin Receptor
- Ephrin Receptor
- Farnesoid X receptor (FXR)
- Glucagon Receptor
Nuclear Receptor Ligands
- Retinoic Acid, X and Orphans Receptors
- Rev-Erb Receptors
- Hepatocyte Nuclear Factors Receptors
- COUP-TF Like Receptors
- Growth Factors Receptors
- Steroid Hormone Receptors
- DAX-Like Receptors
- Vitamin Related Receptors
- PPARs
- DNA Polymerase
- CRFR
- NOD
- RAAS
GDNF Receptors
TNF Receptors
Transcription Factors
Chemokines
- CXCR-2
- CXCR-3
- CXCR-4
- CXCR-7
Cytokine Receptors
- IL Receptors
- Interferon Receptors
- Integrins
- Toll-Like Receptors
- NOD-Like Receptors
Biomarkers and Buffer Solutions
- Universal DNA Markers
- Biological Buffers
- Biomarker
Molecular Probes
- Fluorescence Probes
- Chelating Agents
- Luminescent Probes
- Optical Probes
Stem Cell Research
- Reporter of Gene Expression
- CiPSC Cocktail
  - TSPC - CiPSC Cocktail
  - VC6TF - CiPSC Cocktail
- Complement System
Alzheimer's Disease
Apoptosis
Cancer Research
Epigenetics
Metabolites
PET/SPECT Imaging Precursors
Customized Screening Library
- Target Diversified Drug Like Small Molecule Library
- Target Focused Small Drug Like Molecule Library
Ultra Pure Pharmacological Standard
Tissue Microarray (TMA)
- Bladder
- Brain
- Breast
- Cervix
- Colon
- Digestive Sytem
- Esophagus
- Glucose Test Strips
- Kidney
- Large Intestine
- Liver
- Lung
- Lymphoma
- Multiple Organ
- Multiple Organ IFetus)
- Pancreas
- Prostate
- Rectum
- Reproductive System
- Stomach
- Thyroid
- Urological Sytem
Proteins and Antibodies
- Proteins and Enzymes
  - Cytokines and Chemokines
- Antibodies and Kits
  - RABBIT POLYCLONAL
  - RABBIT MONOCLONAL
- Protein Digestion Sufactant
- Cell Culture
Primary Cells
ELISA KIT
Natural Products
Lab Equipments
Humanized Mice for PDX Platform
Rare Chemicals
Custom Synthesis
Antibacterial
Antifungal
Antioxidant
Antiviral
Molecular Glues
PROTAC Linker
SARS-CoV

View larger

DO34

Cat No: AOB8060

Condition

CAS No: 1848233-58-8

AOBIOUS launched this product in 2018

CITATIONS - Publications That Use AOBIOUS Product

1) JBC 295:8174 (2020)

2) Synaps 2018 Oct 17

3) Neurobiol Stress. 2020 Nov; 13: 100283.

4) Addiction Biology, 26:5 (2021)

5) Neuron 109:2398 (2021)

6) Biorxiv 2020

7) Amer J of Physiol-Cell Physiol 319 (2020)

More details

Print Quotation

Molarity Calculation Cart^®

HOW TO ORDER

Quantity Discount Table - Order More To Get More Price Discount

Quantity	mg	Unit Price ($/mg or $/Unit)	Final Price
1	100	$9.45	Total: $945.00
1	50	$10.92	Total: $546.00
1	25	$12.81	Total: $320.25
1	10	$15.12	Total: $151.20
1	5	$17.85	Total: $89.25

Data sheet

Molecular Formula	C26H28F3N5O4
Molecular Weight	531.54
CAS Numbers	1848233-58-8
Storage Condition	0°C (short term), -20°C (long term), desiccated
Solubility	DMSO
Purity	98% by HPLC
Synonym	DO34; DO-34; DO 34
IUPAC/Chemical Name	3-(Phenylmethyl)-4-[[4-[4-(trifluoromethoxy)phenyl]-1H-1,2,3-triazol-1-yl]carbonyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester
InChl Key	CQGMWUWJVBKTRM-UHFFFAOYSA-N
InChl Code	InChI=1S/C26H28F3N5O4/c1-25(2,3)38-24(36)32-13-14-33(20(16-32)15-18-7-5-4-6-8-18)23(35)34-17-22(30-31-34)19-9-11-21(12-10-19)37-26(27,28)29/h4-12,17,20H,13-16H2,1-3H3
SMILES Code	O=C(N1CC(CC2=CC=CC=C2)N(C(N3N=NC(C4=CC=C(OC(F)(F)F)C=C4)=C3)=O)CC1)OC(C)(C)C
References	1) Deng H, Kooijman S, van den Nieuwendijk AM, Ogasawara D, van der Wel T, van Dalen F, Baggelaar MP, Janssen FJ, van den Berg RJ, den Dulk H, Cravatt BF, Overkleeft HS, Rensen PC, van der Stelt M. Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding. J Med Chem. 2017 Jan 12;60(1):428-440. 2) Liu X, Chen Y, Vickstrom CR, Li Y, Viader A, Cravatt BF, Liu QS. Coordinated regulation of endocannabinoid-mediated retrograde synaptic suppression in the cerebellum by neuronal and astrocytic monoacylglycerol lipase. Sci Rep. 2016 Oct 24;6:35829.