Array
(
)
1
> Epigenetics>GNE-781

Epigenetics

GNE-781 View larger

GNE-781

AOB33320

CAS: 1936422-33-1

 

Chemical Name: 3-(7-(Difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-N-methyl-1-(tetrahydro-2H-pyran-4-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide

More details

1938 Items

Molarity Calculation Cart®

HOW TO ORDER

$49.50

$49.50 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $42.08 Total: $210.38
110 $35.64 Total: $356.40
125 $30.20 Total: $754.88
150 $25.74 Total: $1,287.00
1100 $22.28 Total: $2,227.50

Data sheet

Molecular FormulaC27H33F2N7O2
Molecular Weight525.61
CAS Numbers1936422-33-1
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymGNE-781; GNE 781; GNE781.
IUPAC/Chemical Name3-[7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-N-methyl-1-tetrahydropyran-4-yl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carboxamide
InChl KeyCQCWHSDMJBAGDC-UHFFFAOYSA-N
InChl Code InChI=1S/C27H33F2N7O2/c1-30-27(37)34-9-5-23-22(16-34)26(32-36(23)19-6-10-38-11-7-19)35-8-3-4-17-12-20(18-14-31-33(2)15-18)21(25(28)29)13-24(17)35/h12-15,19,25H,3-11,16H2,1-2H3,(H,30,37)
SMILES CodeO=C(N1CCC(N(C2CCOCC2)N=C3N4CCCC5=C4C=C(C(F)F)C(C6=CN(C)N=C6)=C5)=C3C1)NC
References1) Romero FA, et al GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP). J Med Chem. 2017 Sep 11

More info

Novel Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP)
































Customers who bought this product also bought: