Epigenetics

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Suprastat

AOB14138

CAS 90093-40-6

Chemical Name: 4-((3-(4-(Aminomethyl)phenyl)-1-(4-hydroxybutyl)ureido)methyl)-N-hydroxybenzamide

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$129.00

$129.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $58.05 Total: $5,805.00
150 $67.08 Total: $3,354.00
125 $78.69 Total: $1,967.25
110 $92.88 Total: $928.80
15 $109.65 Total: $548.25

Data sheet

Molecular FormulaC20H26N4O4
Molecular Weight386.45
CAS Numbers90093-40-6
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical Name4-((3-(4-(Aminomethyl)phenyl)-1-(4-hydroxybutyl)ureido)methyl)-N-hydroxybenzamide
InChl KeyVTRGFHYHEAEHGS-UHFFFAOYSA-N
InChl CodeInChI=1S/C20H26N4O4/c21-13-15-5-9-18(10-6-15)22-20(27)24(11-1-2-12-25)14-16-3-7-17(8-4-16)19(26)23-28/h3-10,25,28H,1-2,11-14,21H2,(H,22,27)(H,23,26)
SMILES CodeO=C(NO)C1=CC=C(CN(CCCCO)C(NC2=CC=C(CN)C=C2)=O)C=C1
References1) Satish Noonepalle, et al., Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models, J. Med. Chem. 2020, 63, 18, 10246

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Novel Selective Histone Deacetylase 6 (HDAC6) Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models