Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $194.65 | Total: $973.25 |
| 1 | 10 | $164.88 | Total: $1,648.80 |
| 1 | 25 | $139.69 | Total: $3,492.25 |
| 1 | 50 | $119.08 | Total: $5,954.00 |
| 1 | 100 | $103.05 | Total: $10,305.00 |
Overview
SETDB1-TTD-IN-1 is a potent, selective, and endogenous binder-competitive inhibitor of SETDB1-TTD with a Kd of 88 nM.
Chemical Properties
| Molecular Formula | C28H31N5O2 |
| Molecular Weight | 469.58 |
| CAS Numbers | 2755823-12-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CN1C[C@@H](C[C@@H](C1)c1ccc(OCc2ccccc2)cc1)Nc1nc2cc[nH]c2c(=O)n1CC=C |
Storage and Handling
0C Short Term, -20C Long Term
References
Guo Y, et, al. Structure-Guided Discovery of a Potent and Selective Cell-Active Inhibitor of SETDB1 Tudor Domain. Angew Chem Int Ed Engl. 2021 Apr 12;60[16] 8760-8765.