Function Modulators

UNC7938 View larger

UNC7938

AOB13597

CAS: 1347749-97-6

Chemical Name: UNC10217938; Ethyl (8-((2-(dimethylamino)ethyl)amino)-2,3-diphenylpyrido[2,3-b]pyrazin-6-yl)carbamate


AOBIOUS launched this product in 2020

CITATIONS - Publications That Use AOBIOUS Product

1) Nucleic Acids Research, gkae245 (2024)

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Molarity Calculation Cart®

HOW TO ORDER

$49.00

$49.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $22.05 Total: $2,205.00
150 $25.48 Total: $1,274.00
125 $29.89 Total: $747.25
110 $35.28 Total: $352.80
15 $41.65 Total: $208.25

Data sheet

Molecular FormulaC26H28N6O2
Molecular Weight456.55
CAS Numbers1347749-97-6
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity95% by HPLC
SynonymUNC7938; UNC-7938; UNC 7938; UNC10217938A
IUPAC/Chemical NameEthyl (8-((2-(dimethylamino)ethyl)amino)-2,3-diphenylpyrido[2,3-b]pyrazin-6-yl)carbamate
InChl KeyHHICWLZMNOCMIQ-UHFFFAOYSA-N
InChl CodeInChI=1S/C26H28N6O2/c1-4-34-26(33)29-21-17-20(27-15-16-32(2)3)24-25(28-21)31-23(19-13-9-6-10-14-19)22(30-24)18-11-7-5-8-12-18/h5-14,17H,4,15-16H2,1-3H3,(H2,27,28,29,31,33)
SMILES CodeO=C(OCC)NC1=CC(NCCN(C)C)=C2C(N=C(C3=CC=CC=C3)C(C4=CC=CC=C4)=N2)=N1
References1) Jason Allen et al., Cytosolic Delivery of Macromolecules in Live Human Cells Using the Combined Endosomal Escape Activities of a Small Molecule and Cell Penetrating Peptides, ACS Chem. Biol. 2019, 14, 12, 2641–2651

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Novel destabilizer of the endosome membrane, enhancing the endosome-leakage activity of cell-penetrating peptides and facilitating the endosomal escape of macromolecules initially internalized by mammalian cells via endocytosis

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