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Function Modulators
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VISTA modulator 6809-0223
AOB14462
CAS: 669749-25-1
Chemical Name: 2-((4,6-Dimethylquinazolin-2-yl)amino)-6-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)pyrimidin-4(3H)-one
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $58.05 | Total: $5,805.00 |
| 1 | 50 | $67.08 | Total: $3,354.00 |
| 1 | 25 | $78.69 | Total: $1,967.25 |
| 1 | 10 | $92.88 | Total: $928.80 |
| 1 | 5 | $109.65 | Total: $548.25 |
Data sheet
| Molecular Formula | C18H17N7OS2 |
| Molecular Weight | 411.50 |
| CAS Numbers | 669749-25-1 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | VISTA modulator 6809-0223; VISTA modulator 68090223; VISTA modulator 6809 0223; |
| IUPAC/Chemical Name | 2-((4,6-dimethylquinazolin-2-yl)amino)-6-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)pyrimidin-4(3H)-one |
| InChl Key | YIJOQQHVEVIMNS-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C18H17N7OS2/c1-9-4-5-14-13(6-9)10(2)19-16(21-14)23-17-20-12(7-15(26)22-17)8-27-18-25-24-11(3)28-18/h4-7H,8H2,1-3H3,(H2,19,20,21,22,23,26) |
| SMILES Code | O=C1NC(NC2=NC(C)=C3C=C(C)C=CC3=N2)=NC(CSC4=NN=C(C)S4)=C1 |
| References | 1) Zong L, Yu S, Mo S, Zhou Y, Xiang Y, Lu Z, Chen J. High VISTA Expression Correlates With a Favorable Prognosis in Patients With Colorectal Cancer. J Immunother. 2021 Jan;44(1):22-28. |
More info
Novel immune checkpoint VISTA (V-domain immunoglobulin suppressor of T-cell activation) modulator