G Protein-Coupled Receptor Ligands

10-Cl-BBQ View larger

10-Cl-BBQ

AOB2641

CAS: 23982-76-5

 

Chemical Name: 10-Chloro-7H-benzimidazo[2,1-a]benzo[de]Iso-quinolin-7-one

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Quantity Discount Table - Order More To Get More Price Discount

Quantity (mg or Unit)Unit Price ($/mg or $/Unit)Final Price
100 $6.75 Total: $675.00
50 $7.80 Total: $390.00
25 $9.15 Total: $228.75
10 $10.80 Total: $108.00
5 $12.75 Total: $63.75

Data sheet

Molecular FormulaC18H9ClN2O
Molecular Weight304.73
CAS Numbers23982-76-5
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical Name10-Chloro-7H-benzimidazo[2,1-a]benz[de]isoquinolin-7-one
InChl KeyZJESJVGSDQOZAT-UHFFFAOYSA-N
SMILES CodeClC1=CC2=C(N=C3N2C(C4=CC=CC5=C4C3=CC=C5)=O)C=C1
References1) Punj et al (2014) Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease. PLoS One 9 e88726 PMID: 24586378

2) Ehrlich et al (2016) Activation of the aryl hydrocarbon receptor by 10-Cl-BBQ prevents insulitis and effector T cell development independently of Foxp3+ regulatory T Cells in nonobese diabetic mice. J.Immunol. 196 264 PMID: 26573835
PubChem ID1778614

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Potent aryl hydrocarbon receptor (AhR) ligand











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