GNE-9822

L-165041

AOB6776

CAS: 79558-09-1

 

Chemical Name: 2-(4-(3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propoxy)phenoxy)acetic acid

More details

1000 Items

$15.00

$15.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $12.75 Total: $63.75
110 $10.80 Total: $108.00
125 $9.15 Total: $228.75
150 $7.80 Total: $390.00
1100 $6.75 Total: $675.00

Overview

Potent PPARδ agonist, inhibiting VEGF-induced angiogenesis not related to PPARδ

Chemical Properties

Molecular FormulaC22H26O7
Molecular Weight402.44
CAS Numbers79558-09-1
SolubilityDMSO: >10 mg/mL
Purity98% by HPLC
IUPAC/Chemical Name4-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy­acetic acid
InChl KeyYBEZORYMVISYOA-UHFFFAOYSA-N
InChl CodeInChI=1S/C22H26O7/c1-3-5-19-20(11-10-18(15(2)23)22(19)26)28-13-4-12-27-16-6-8-17(9-7-16)29-14-21(24)25/h6-11,26H,3-5,12-14H2,1-2H3,(H,24,25)
SMILES CodeCCCc1c(O)c(ccc1OCCCOc2ccc(OCC(O)=O)cc2)C(C)=O
PubChem ID4364841

Storage and Handling

0°C (short term), -20°C (long term), desiccated

Synonyms

L165041; L 165041

References

1) Berger et al (1999) Novel peroxisome proliferator-activated receptor (PPAR)γ and PPARδ ligands produce distinct biological effects. J.Biol.Chem. 274 6718 PMID: 10037770

2) Iwashita et al (2007) Neuroprotective efficacy of the peroxisome proliferator-activated receptor δ-selective agonists in vitro and in vivo. J.Pharmacol.Exp.Ther. 320 1087 PMID: 17167170

3) Leibowitz et al (2000) Activation of PPARδ alters lipid metabolism in db/db mice. FEBS Lett. 473 333 PMID: 10818235