G Protein-Coupled Receptor Ligands

TAK-242 View larger

LY6

AOB17121

CAS: 2296718-09-5

 

Chemical Name: (E)-1-(1-(5-(3-(2,4-Dichlorophenyl)acryloyl)-2-ethoxy-4-hydroxybenzyl)-1,2,5,6-tetrahydropyridin-3-yl)-1H-benzo[d]imidazol-2(3H)-one

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$129.00

$129.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $58.05 Total: $5,805.00
150 $67.08 Total: $3,354.00
125 $78.69 Total: $1,967.25
110 $92.88 Total: $928.80
15 $109.65 Total: $548.25

Data sheet

Molecular FormulaC30H27Cl2N3O4
Molecular Weight564.46
CAS Numbers2296718-09-5
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical Name (E)-1-(1-(5-(3-(2,4-Dichlorophenyl)acryloyl)-2-ethoxy-4-hydroxybenzyl)-1,2,5,6-tetrahydropyridin-3-yl)-1H-benzo[d]imidazol-2(3H)-one
References1) Xiaoqin Wu et al., A small molecule inhibitor that stabilizes the autoinhibited conformation of the oncogenic tyrosine phosphatase SHP2, J Med Chem. 2019 Feb 14; 62(3): 1125–1137.

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Novel SHP2 inhibitor, stabilizing the autoinhibited conformation of the oncogenic tyrosine phosphatase SHP2