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View larger AOB17121
CAS: 2296718-09-5
Chemical Name: (E)-1-(1-(5-(3-(2,4-Dichlorophenyl)acryloyl)-2-ethoxy-4-hydroxybenzyl)-1,2,5,6-tetrahydropyridin-3-yl)-1H-benzo[d]imidazol-2(3H)-one
996 Items
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $109.65 | Total: $548.25 |
| 1 | 10 | $92.88 | Total: $928.80 |
| 1 | 25 | $78.69 | Total: $1,967.25 |
| 1 | 50 | $67.08 | Total: $3,354.00 |
| 1 | 100 | $58.05 | Total: $5,805.00 |
| Molecular Formula | C30H27Cl2N3O4 |
| Molecular Weight | 564.46 |
| CAS Numbers | 2296718-09-5 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (E)-1-(1-(5-(3-(2,4-Dichlorophenyl)acryloyl)-2-ethoxy-4-hydroxybenzyl)-1,2,5,6-tetrahydropyridin-3-yl)-1H-benzo[d]imidazol-2(3H)-one |
| References | 1) Xiaoqin Wu et al., A small molecule inhibitor that stabilizes the autoinhibited conformation of the oncogenic tyrosine phosphatase SHP2, J Med Chem. 2019 Feb 14; 62(3): 1125–1137. |
Novel SHP2 inhibitor, stabilizing the autoinhibited conformation of the oncogenic tyrosine phosphatase SHP2