G Protein-Coupled Receptor Ligands

NSC47924 View larger

NSC47924

AOB9607

CAS No: 6638-24-0

 

Chemical Name: 1-((4-Methoxyanilino)methyl)-2-naphthol

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$17.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $7.65 Total: $765.00
150 $8.84 Total: $442.00
125 $10.37 Total: $259.25
110 $12.24 Total: $122.40
15 $14.45 Total: $72.25

Data sheet

Molecular FormulaC18H17NO2
Molecular Weight279.33
CAS Numbers6638-24-0
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymNSC47924; NSC-47924; NSC 47924
IUPAC/Chemical Name1-((4-Methoxyanilino)methyl)-2-naphthol
InChl KeyIBZVGAKJSAZIAB-UHFFFAOYSA-N
InChl CodeInChI=1S/C18H17NO2/c1-21-15-9-7-14(8-10-15)19-12-17-16-5-3-2-4-13(16)6-11-18(17)20/h2-11,19-20H,12H2,1H3
SMILES CodeOC1=CC=C2C=CC=CC2=C1CNC3=CC=C(OC)C=C3
References1) Sarnataro D, Pepe A, Altamura G, De Simone I, Pesapane A, Nitsch L, Montuori N, Lavecchia A, Zurzolo C. The 37/67 kDa laminin receptor (LR) inhibitor, NSC47924, affects 37/67 kDa LR cell surface localization and interaction with the cellular prion protein. Sci Rep. 2016 Apr 13;6:24457.

2) Pesapane A, Di Giovanni C, Rossi FW, Alfano D, Formisano L, Ragno P, Selleri C, Montuori N, Lavecchia A. Discovery of new small molecules inhibiting 67 kDa laminin receptor interaction with laminin and cancer cell invasion. Oncotarget. 2015 Jul 20;6(20):18116-33

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Novel 37/67kDa laminin receptor (LR) inhibitor, affecting both the direct 37/67kDa LR-PrP(C) interaction in vitro and the formation of the immunocomplex in live cells, inducing a progressive internalization of 37/67kDa LR and stabilization of PrP(C) on the cell surface

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