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View larger NSC47924
AOB9607
CAS No: 6638-24-0
Chemical Name: 1-((4-Methoxyanilino)methyl)-2-naphthol
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| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $12.75 | Total: $63.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 100 | $6.75 | Total: $675.00 |
Data sheet
| Molecular Formula | C18H17NO2 |
| Molecular Weight | 279.33 |
| CAS Numbers | 6638-24-0 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | NSC47924; NSC-47924; NSC 47924 |
| IUPAC/Chemical Name | 1-((4-Methoxyanilino)methyl)-2-naphthol |
| InChl Key | IBZVGAKJSAZIAB-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C18H17NO2/c1-21-15-9-7-14(8-10-15)19-12-17-16-5-3-2-4-13(16)6-11-18(17)20/h2-11,19-20H,12H2,1H3 |
| SMILES Code | OC1=CC=C2C=CC=CC2=C1CNC3=CC=C(OC)C=C3 |
| References | 1) Sarnataro D, Pepe A, Altamura G, De Simone I, Pesapane A, Nitsch L, Montuori N, Lavecchia A, Zurzolo C. The 37/67 kDa laminin receptor (LR) inhibitor, NSC47924, affects 37/67 kDa LR cell surface localization and interaction with the cellular prion protein. Sci Rep. 2016 Apr 13;6:24457. 2) Pesapane A, Di Giovanni C, Rossi FW, Alfano D, Formisano L, Ragno P, Selleri C, Montuori N, Lavecchia A. Discovery of new small molecules inhibiting 67 kDa laminin receptor interaction with laminin and cancer cell invasion. Oncotarget. 2015 Jul 20;6(20):18116-33 |
More info
Novel 37/67kDa laminin receptor (LR) inhibitor, affecting both the direct 37/67kDa LR-PrP(C) interaction in vitro and the formation of the immunocomplex in live cells, inducing a progressive internalization of 37/67kDa LR and stabilization of PrP(C) on the cell surface
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