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View larger Dersimelagon
AT25310
CAS 1835256-48-8
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $51.85 | Total: $259.25 |
| 1 | 10 | $43.92 | Total: $439.20 |
| 1 | 25 | $37.21 | Total: $930.25 |
| 1 | 50 | $31.72 | Total: $1,586.00 |
| 1 | 100 | $27.45 | Total: $2,745.00 |
Data sheet
| Molecular Formula | C36H45F4N3O5 |
| Molecular Weight | 675.75 |
| CAS Numbers | 1835256-48-8 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(=O)([C@@]1(F)[C@@H](CN(C1)C2CCCC2)C3=CC=C(OC)C=C3)N4C[C@@H]([C@@H](COC)C4)C5=C(C=C(C(F)(F)F)C=C5)N6CCC(C(O)=O)CC6 |
| References | T. Suzuki, et al. Melanogenic effect of dersimelagon [MT-7117], a novel oral melanocortin 1 receptor agonist. Skin Health Dis. 2022; 2[1] e78. |
More info
Dersimelagon (MT-7117) is an orally active, selective agonist for the melanocortin 1 receptor (MC1R), with EC50 values of 8.16 nM (h), 3.91 nM (cm), 1.14 nM (m), and 0.251 nM (r) in human, cynomolgus monkey, mouse, and rat, respectively. It exhibits strong affinity for human MC1R and MC4R, with Ki values of 2.26 nM and 32.9 nM, respectively. The compound is used in the study of skin pigmentation.