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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $51.85 | Total: $259.25 |
| 1 | 10 | $43.92 | Total: $439.20 |
| 1 | 25 | $37.21 | Total: $930.25 |
| 1 | 50 | $31.72 | Total: $1,586.00 |
| 1 | 100 | $27.45 | Total: $2,745.00 |
Overview
Dersimelagon (MT-7117) is an orally active, selective agonist for the melanocortin 1 receptor (MC1R), with EC50 values of 8.16 nM (h), 3.91 nM (cm), 1.14 nM (m), and 0.251 nM (r) in human, cynomolgus monkey, mouse, and rat, respectively. It exhibits strong affinity for human MC1R and MC4R, with Ki values of 2.26 nM and 32.9 nM, respectively. The compound is used in the study of skin pigmentation.
Chemical Properties
| Molecular Formula | C36H45F4N3O5 |
| Molecular Weight | 675.75 |
| CAS Numbers | 1835256-48-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(=O)([C@@]1(F)[C@@H](CN(C1)C2CCCC2)C3=CC=C(OC)C=C3)N4C[C@@H]([C@@H](COC)C4)C5=C(C=C(C(F)(F)F)C=C5)N6CCC(C(O)=O)CC6 |
Storage and Handling
0C Short Term, -20C Long Term
References
T. Suzuki, et al. Melanogenic effect of dersimelagon [MT-7117], a novel oral melanocortin 1 receptor agonist. Skin Health Dis. 2022; 2[1] e78.