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GABA Receptors
- Protein Control Ligand
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View larger Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $11.70 | Total: $1,170.00 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 5 | $22.10 | Total: $110.50 |
Data sheet
| Molecular Formula | C17H19ClN2O4 |
| Molecular Weight | 350.8 |
| CAS Numbers | 1215833-62-7 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.CCc1c(ncc2[nH]c3cc(OC)c(OC)cc3c12)C(=O)OC |
| References | Chambers MS, et al. An orally bioavailable, functionally selective inverse agonist at the benzodiazepine site of GABAA alpha5 receptors with cognition enhancing properties. J Med Chem. 2004 Nov 18;47[24] 5829-32. |
More info
DMCM hydrochloride is a non-selective fully inverse agonist of benzodiazepine. DMCM showed significant differences in human recombinant GABAA ?x?3?2 receptor subtypes. For ?1, ?2, ?3, and ?5 receptors, their Kis were 10 nM, 13 nM, 7.5 nM, 2.2 nM, respectively.