Growth Factors Receptors

AZ7550 hydrochloride View larger

AZ7550 hydrochloride

AT13564L

CAS 2309762-40-9

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$107.00

$107.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $48.15 Total: $4,815.00
150 $55.64 Total: $2,782.00
125 $65.27 Total: $1,631.75
110 $77.04 Total: $770.40
15 $90.95 Total: $454.75

Data sheet

Molecular FormulaC27H32ClN7O2
Molecular Weight522.04
CAS Numbers2309762-40-9
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC=CC(NC1=CC(NC2=NC=CC(C3=CN(C4=C3C=CC=C4)C)=N2)=C(C=C1N(CCNC)C)OC)=O.[H]Cl
ReferencesFinlay MR, et al. Discovery of a potent and selective EGFR inhibitor [AZD9291] of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor. J Med Chem. 2014 Oct 23;57[20] 8249-67.

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AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 ?M).