Growth Factors Receptors

Larotinib View larger

Larotinib

AT73334

CAS 1438072-11-7

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$63.00

$63.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $28.35 Total: $2,835.00
150 $32.76 Total: $1,638.00
125 $38.43 Total: $960.75
110 $45.36 Total: $453.60
15 $53.55 Total: $267.75

Data sheet

Molecular FormulaC24H26ClFN4O4
Molecular Weight488.94
CAS Numbers1438072-11-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeN(C=1C2=C(C=C(OC)C(OCCCN3C[C@@]4([C@](C3)(OCCO4)[H])[H])=C2)N=CN1)C5=CC(Cl)=C(F)C=C5
ReferencesLiu J, et al. Phase I Trial to Evaluate the Tolerance, Pharmacokinetics and Efficacy of the Broad-Spectrum ErbB Family Inhibitor Larotinib Mesylate in Patients With Advanced Solid Tumors. Front Pharmacol. 2021;12 636324.

More info

Larotinib is an orally active, potent, and broad-spectrum tyrosine kinase inhibitor (TKI) with an IC50 of 0.6 nM for EGFR.