Histamine Receptors

Dalcotidine View larger

Dalcotidine

AT31195

CAS 120958-90-9

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$122.00

$122.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $54.90 Total: $5,490.00
150 $63.44 Total: $3,172.00
125 $74.42 Total: $1,860.50
110 $87.84 Total: $878.40
15 $103.70 Total: $518.50

Data sheet

Molecular FormulaC18H29N3O2
Molecular Weight319.44
CAS Numbers120958-90-9
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(C1=CC(OCCCNC(NCC)=O)=CC=C1)N2CCCCC2
ReferencesSekiguchi H, et al. Pharmacological profiles of the new histamine H2-receptor antagonist N-ethyl-N'-[3-[3-[piperidinomethyl]phenoxy] propyl] urea. Arzneimittelforschung. 1993;43[2] 129-133.

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Dalcotidine (KU 1257) is a novel histamine H2 receptor antagonist with histamine H9 receptor antagonistic activity and antisecretory effects.The Ki value for binding to guinea pig cerebral cortex was 0.040 The KB value for antagonism of histamine-induced positive chronotropic responses in the right atrium of isolate guinea pigs was 0.041.Dalcotidine improves the quality of ulcer healing, and may contribute to a reduction in ulcer recurrence and relapse rates.