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Hydroxylases
- Protein Control Ligand
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- Kinase Inhibitors
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- β-arrestin/β2-adaptin
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View larger Belzutifan
AT16679
CAS 1672668-24-4
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $45.90 | Total: $229.50 |
| 1 | 10 | $38.88 | Total: $388.80 |
| 1 | 25 | $32.94 | Total: $823.50 |
| 1 | 50 | $28.08 | Total: $1,404.00 |
| 1 | 100 | $24.30 | Total: $2,430.00 |
Data sheet
| Molecular Formula | C17H12F3NO4S |
| Molecular Weight | 383.34 |
| CAS Numbers | 1672668-24-4 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CS(=O)(=O)c1ccc(Oc2cc(F)cc(c2)C#N)c2[C@@H](F)[C@@H](F)[C@@H](O)c12 |
| References | Xu R, et al. 3-[[1S,2S,3R]-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl]oxy-5-fluorobenzonitrile [PT2977], a Hypoxia-Inducible Factor 2? [HIF-2?] Inhibitor for the Treatment of Clear Cell Renal Cell Carcinoma. J Med Chem. 2019 Aug 8;62[15] 6876-6893. |
More info
Belzutifan (MK-6482) is a potential treatment for clear cell renal cell carcinoma (ccRCC). Belzutifan is an orally active and selective HIF-2? inhibitor (IC50: 9 nM). Belzutifan , as a second-generation HIF-2? inhibitor, increases potency and improves pharmacokinetic profile.