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View larger Inosine pranobex
AT3614
CAS 36703-88-5
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Data sheet
| Molecular Formula | C52H78N10O17 |
| Molecular Weight | 1115.23 |
| CAS Numbers | 36703-88-5 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(O)CN(C)C.CC(O)CN(C)C.CC(O)CN(C)C.CC(=O)Nc1ccc(cc1)C(O)=O.CC(=O)Nc1ccc(cc1)C(O)=O.CC(=O)Nc1ccc(cc1)C(O)=O.OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c1nc[nH]c2=O |
| References | Beran J, et al. BMC Infect Dis. 2016; 16 648. |
More info
Inosine pranobex (Delimmun) has a number of immunomodulatory effects, including inducing T-lymphocyte differentiation, augmenting macrophage and NK cell functions, and stimulating IL-2 production. Through these effects and others, isoprinosine shows antiviral activity and has applications against subacute sclerosing panencephalitis. It also restores depressed immune responses in Y patients after irradiation and reduces the incidence of infection in leukemia patients undergoing chemotherapy. It is most commonly used to treat the rare measles complication subacute sclerosing panencephalitis in conjunction with intrathecal interferon therapy.