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> Pathway Inhibitors>Enzyme Inhibitors>Kinase Inhibitors>KHK-IN-2

Kinase Inhibitors

KHK-IN-2 View larger

KHK-IN-2

AOB17831

CAS: 2135304-43-5

Chemical Name: 6-((3S,4S)-3,4-Dihydroxypyrrolidin-1-yl)-2-((S)-3-hydroxy-3-methylpyrrolidin-1-yl)-4-(trifluoromethyl)nicotinonitrile

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$37.50

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QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $31.88 Total: $159.38
110 $27.00 Total: $270.00
125 $22.88 Total: $571.88
150 $19.50 Total: $975.00
1100 $16.88 Total: $1,687.50

Data sheet

Molecular FormulaC16H19F3N4O3
Molecular Weight372.35
CAS Numbers2135304-43-5
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical Name6-((3S,4S)-3,4-Dihydroxypyrrolidin-1-yl)-2-((S)-3-hydroxy-3-methylpyrrolidin-1-yl)-4-(trifluoromethyl)nicotinonitrile
SMILES CodeN#CC1=C(C(F)(F)F)C=C(N2C[C@H](O)[C@@H](O)C2)N=C1N3CC[C@](C)(O)C3
References1) Huard K, et al. Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK). J Med Chem. 2017 Sep 28;60(18):7835-7849.

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Novel potent and selective inhibitor of ketohexokinase (KHK)