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> Pathway Inhibitors>Enzyme Inhibitors>Kinase Inhibitors>FRAX1036 dihydrochloride

Kinase Inhibitors

FRAX1036 dihydrochloride View larger

FRAX1036 dihydrochloride

AOB16925G

CAS: 1432908-05-8 (free base)

 

Chemical Name: 6-[2-Chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-[2-(1-methylpiperidin-4-yl)ethylamino]pyrido[2,3-d]pyrimidin-7-one dihydrochloride

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Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $12.75 Total: $63.75
110 $10.80 Total: $108.00
125 $9.15 Total: $228.75
150 $7.80 Total: $390.00
1100 $6.75 Total: $675.00

Data sheet

Molecular FormulaC28H32ClN7O 2HCl
Molecular Weight590.98
CAS Numbers1432908-05-8 (free base)
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymFRAX1036; FRAX-1036; FRAX 1036.
IUPAC/Chemical Name6-(2-chloro-4-(6-methylpyrazin-2-yl)phenyl)-8-ethyl-2-((2-(1-methylpiperidin-4-yl)ethyl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
InChl KeyRYCBSFIKWACFBY-UHFFFAOYSA-N
InChl CodeInChI=1S/C28H32ClN7O/c1-4-36-26-21(16-32-28(34-26)31-10-7-19-8-11-35(3)12-9-19)13-23(27(36)37)22-6-5-20(14-24(22)29)25-17-30-15-18(2)33-
SMILES CodeO=C1C(C2=CC=C(C3=NC(C)=CN=C3)C=C2Cl)=CC4=CN=C(NCCC5CCN(C)CC5)N=C4N1CC
References1) Mortazavi F, Lu J, Phan R, Lewis M, Trinidad K, Aljilani A, Pezeshkpour G, Tamanoi F. Significance of KRAS/PAK1/Crk pathway in non-small cell lung cancer oncogenesis. BMC Cancer. 2015 May 9;15:381. doi: 10.1186/s12885-015-1360-4. PubMed PMID: 25956913; PubMed Central PMCID: PMC4477307.13.

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