Kinase Inhibitors

Aurora kinase inhibitor-3 View larger

Aurora kinase inhibitor-3

AT5524

CAS 879127-16-9

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$60.00

$60.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $27.00 Total: $2,700.00
150 $31.20 Total: $1,560.00
125 $36.60 Total: $915.00
110 $43.20 Total: $432.00
15 $51.00 Total: $255.00

Data sheet

Molecular FormulaC21H18F3N5O
Molecular Weight413.4
CAS Numbers879127-16-9
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeFC(F)(F)c1cccc(Nc2ccnc(Nc3cccc(NC(=O)C4CC4)c3)n2)c1
ReferencesZhang Q , Liu Y , Gao F , et al. Discovery of EGFR Selective 4,6-Disubstituted Pyrimidines from a Combinatorial Kinase-Directed Heterocycle Library[J]. Journal of the American Chemical Society, 2006, 128[7] 2182-2183.

More info

Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR.