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View larger PROTAC BRAF-V600E degrader-1
AT8745
CAS 2417296-84-3
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $137.70 | Total: $688.50 |
| 1 | 10 | $116.64 | Total: $1,166.40 |
| 1 | 25 | $98.82 | Total: $2,470.50 |
| 1 | 50 | $84.24 | Total: $4,212.00 |
| 1 | 100 | $72.90 | Total: $7,290.00 |
Data sheet
| Molecular Formula | C48H54F2N10O10S |
| Molecular Weight | 1001.07 |
| CAS Numbers | 2417296-84-3 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | FC1=C(N2C=3C(C(=C2)C=4C=NC=NC4)=NC(N(C)C5CCN(C(CCOCCOCCOCCNC6=C7C(C(=O)N(C7=O)C8C(=O)NC(=O)CC8)=CC=C6)=O)CC5)=CC3)C(F)=CC=C1NS(CCC)(=O)=O |
| References | Han X R , Chen L , Wei Y , et al. Discovery of Selective Small Molecule Degraders of BRAF-V600E[J]. Journal of Medicinal Chemistry, 2020, XXXX[XXX]. |
More info
PROTAC BRAF-V600E degrader-1 (Compound 23) selectively induces degradation of BRAF-V600E but not wildtype BRAF.