Kinase Inhibitors

Casein kinase 1?-IN-6 View larger

Casein kinase 1?-IN-6

AT77500

CAS 1579991-01-7

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$110.00

$110.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $49.50 Total: $4,950.00
150 $57.20 Total: $2,860.00
125 $67.10 Total: $1,677.50
110 $79.20 Total: $792.00
15 $93.50 Total: $467.50

Data sheet

Molecular FormulaC16H10ClF3N2OS
Molecular Weight370.78
CAS Numbers1579991-01-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeN(C(CC1=CC(Cl)=CC=C1)=O)C=2SC=3C(N2)=CC=C(C(F)(F)F)C3
ReferencesMorales-Garcia JA, et al. Biological and Pharmacological Characterization of Benzothiazole-Based CK-1? Inhibitors in Models of Parkinson's Disease. ACS Omega. 2017;2[8] 5215-5220.

More info

Casein kinase 1?-IN-6 is a potent and selective inhibitor of the protein kinase CK-1? with an IC50 of 23 nM, demonstrating neuroprotective and anti-inflammatory activity in both in vitro and in vivo assays. Casein kinase 1?-IN-6 can be used to study neurodegenerative diseases.