> G Protein-Coupled Receptor Ligands>Neuropeptide Receptors>[Sar9,Met(O2)11]-Substance P acetate

Neuropeptide Receptors

[Sar9,Met(O2)11]-Substance P acetate View larger

[Sar9,Met(O2)11]-Substance P acetate

ATP1369L

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$78.00

$78.00 per mg

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Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $35.10 Total: $3,510.00
150 $40.56 Total: $2,028.00
125 $47.58 Total: $1,189.50
110 $56.16 Total: $561.60
15 $66.30 Total: $331.50

Data sheet

Molecular FormulaC67H106N18O17S
Molecular Weight1467.75
CAS Numbers3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C([C@H](CCCCN)NC([C@H]1N(C([C@@H](N)CCCNC(N)=N)=O)CCC1)=O)N(CCC2)[C@@H]2C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@H](C(N(C)CC(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCS(C)(=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)CC4=CC=CC=C4)=O)=O)=O.CC(O)=C.[O]
ReferencesCellier E, et al. Characterization of central and peripheral effects of septide with the use of five tachykinin NK1 receptor antagonists in the rat. Br J Pharmacol. 1999 Jun;127[3] 717-28.

More info

[Sar9,Met(O2)11]-Substance P acetate is a tachykinin NK1 receptor selective agonist. [Sar9,Met(O2)11]-Substance P acetate is a selective tachykinin NK1 receptor agonist.[Sar9,Met(O2)11]-Substance P acetate and septide (10-100 pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and heart rate (HR), yet they have dissimilar time-course. Both agonists increase dose-dependently face washing and sniffing while [Sar9,Met(O2)11]-Substance P acetate is the sole to produce grooming.