Neuropeptide Receptors

RFRP-1 (human) acetate(311309-25-8 free base) View larger

RFRP-1 (human) acetate(311309-25-8 free base)

ATP1937L1

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$113.00

$113.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $50.85 Total: $5,085.00
150 $58.76 Total: $2,938.00
125 $68.93 Total: $1,723.25
110 $81.36 Total: $813.60
15 $96.05 Total: $480.25

Data sheet

Molecular FormulaC69H105N19O16S
Molecular Weight1488.77
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeNC([C@H](CC1=CC=CC=C1)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H]2N(CCC2)C([C@H](CC(C)C)NC([C@H](CC(N)=O)NC([C@H](C)NC([C@@H](NC([C@H](CO)NC([C@H](CC3=CN=CN3)NC([C@H]4N(CCC4)C([C@@H](N)CCSC)=O)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)=O)=O.CC(O)=O
ReferencesGouardères et al [2006] Functional differences between NPFF1 and NPFF2 receptor coupling high intrinsic activities of RFamide-related peptides on stimulation of [35S]GTPγS binding. Neuropharmacology 52 376 PMID

More info

RFRP-1 (human) acetate is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume, ejection fraction and cardiac output, and increases plasma prolactin levels in rats. GnIH homolog.