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> G Protein-Coupled Receptor Ligands>Neuropeptide Receptors>Urantide acetate(669089-53-6 free base)

Neuropeptide Receptors

Urantide acetate(669089-53-6 free base) View larger

Urantide acetate(669089-53-6 free base)

ATP2106L

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$98.00

$98.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $83.30 Total: $416.50
110 $70.56 Total: $705.60
125 $59.78 Total: $1,494.50
150 $50.96 Total: $2,548.00
1100 $44.10 Total: $4,410.00

Data sheet

Molecular FormulaC53H70N10O14S2
Molecular Weight1135.31
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC([C@@H](C(O)=O)NC([C@@H]1CSSC(C)([C@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N1)=O)Cc2ccc(O)cc2)=O)CCCN)=O)Cc(c[nH]3)c4c3cccc4)=O)Cc5ccccc5)=O)NC([C@H](CC(O)=O)N)=O)C)=O)C.CC(O)=O
ReferencesPatacchini et al [2003] Urantide an ultrapotent urotensin II antagonist peptide in the rat aorta. Br.J.Pharmacol. 140 1155 PMID

More info

Urantide acetate is a selective and competitive urotensin-II (UT) receptor antagonist (pKB = 8.3). Blocks hU-II induced contractions in thoracic aorta ex vivo. Exhibits no effect on noradrenaline or endothelin 1-induced contraction or on acetylcholine-induced relaxation. Behaves as a partial agonist in a calcium mobilization assay (in CHO cells expressing hUT receptors).