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Overview
Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. Rifaximin binds to the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting bacterial RNA synthesis and bacterial cell growth.
Chemical Properties
| Molecular Formula | C43H51N3O11 |
| Molecular Weight | 785.88 |
| CAS Numbers | 80621-81-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COC1C=COC2(C)OC3=C(C2=O)C2=C(C(O)=C3C)C(O)=C(NC(=O)C(C)=CC=CC(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C)C1=C2N=C2C=C(C)C=CN12 |
Storage and Handling
0C Short Term, -20C Long Term
References
Mencarelli A, et al. Eur J Pharmacol,2011, 668[1-2], 317-324.