Opioid Receptors

Ro-64-6198 View larger

Ro-64-6198

AOB3906

CAS: 280783-56-4

Chemical Name: Ro64-6198; 8-[(1S,3aS)-2,3,3a,4,5,6-Hexahydro-1H-phenalen-1-yl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one

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$25.00

$25.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $11.25 Total: $1,125.00
150 $13.00 Total: $650.00
125 $15.25 Total: $381.25
110 $18.00 Total: $180.00
15 $21.25 Total: $106.25

Data sheet

Molecular FormulaC26H31N3O
Molecular Weight401.55
CAS Numbers280783-56-4
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymRo64-6198; Ro 64-6198; Ro-64-6198.
IUPAC/Chemical Name8-[(1S,3aS)-2,3,3a,4,5,6-hexahydro-1H-phenalen-1-yl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
InChl KeyJLFMYEAXZNPWBK-REWPJTCUSA-N
InChl CodeInChI=1S/C26H31N3O/c30-25-26(29(18-27-25)21-9-2-1-3-10-21)14-16-28(17-15-26)23-13-12-20-7-4-6-19-8-5-11-22(23)24(19)20/h1-3,5,8-11,20,23H,4,6-7,12-18H2,(H,27,30)/t20-,23-/m0/s1
SMILES CodeO=C1NCN(C2=CC=CC=C2)C13CCN([C@H]4CC[C@]5([H])CCCC6=CC=CC4=C56)CC3
References1) Reiss D, Prinssen EP, Wichmann J, Kieffer BL, Ouagazzal AM. The nociceptin orphanin FQ peptide receptor agonist, Ro64-6198, impairs recognition memory formation through interaction with glutamatergic but not cholinergic receptor antagonists. Neurobiol Learn Mem. 2012 Oct;98(3):254-60.

2) Reiss D, Wichmann J, Tekeshima H, Kieffer BL, Ouagazzal AM. Effects of nociceptin/orphanin FQ receptor (NOP) agonist, Ro64-6198, on reactivity to acute pain in mice: comparison to morphine. Eur J Pharmacol. 2008 Jan 28;579(1-3):141-8. Epub 2007 Oct 25. PubMed PMID: 18031727.

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Nociceptin/orphanin FQ peptide receptor agonist; Nonpeptide selective NOP receptor (opiate receptor-like 1, ORL-1) agonist

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