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Opioid Receptors
- Protein Control Ligand
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View larger Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $40.95 | Total: $4,095.00 |
| 1 | 50 | $47.32 | Total: $2,366.00 |
| 1 | 25 | $55.51 | Total: $1,387.75 |
| 1 | 10 | $65.52 | Total: $655.20 |
| 1 | 5 | $77.35 | Total: $386.75 |
Data sheet
| Molecular Formula | C25H32FN5O2 |
| Molecular Weight | 453.55 |
| CAS Numbers | 2244614-14-8 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCc1cc(F)c2nc(N3CCC(CC3)NC3CCOCC3)c(-c3nc(C)no3)c(C)c2c1 |
| References | Guerrero M, et al. Design and Synthesis of a Novel and Selective Kappa Opioid Receptor [KOR] Antagonist [BTRX-335140]. J Med Chem. 2019 Feb 28;62[4] 1761-1780. |
More info
BTRX-335140 (CYM-53093) is a potent and selective, orally active ? opioid receptor (KOR) antagonist, has antagonist activity for ?OR, ?OR and ?OR with IC50 values of 0.8 nM, 110 nM, and 6500 nM, respectively. BTRX-335140 can distribute well into the CNS. ADMET (absorption, distribution, metabolism, excretion, and toxicity) . BTRX-335140 endows with favorable in vitro ADMET and in vivo pharmacokinetic profiles and medication-like duration of action in rats.