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J014
AOB13366
CAS: N/A
Chemical Name: 4-Nitro-N-(4-phenylpyridin-2-yl)-1H-pyrazole-5-carboxamide
124 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $23.37 | Total: $116.87 |
| 1 | 10 | $19.80 | Total: $198.00 |
| 1 | 25 | $16.78 | Total: $419.38 |
| 1 | 50 | $14.30 | Total: $715.00 |
| 1 | 100 | $12.38 | Total: $1,237.50 |
Overview
Novel cGAS-specific inhibitor for repression of dsDNA-triggered interferon expression ( IC50 of 100 nM and 60.0 nM for h-cGAS and m-cGAS, respectively)
Chemical Properties
| Molecular Formula | C15H11N5O3 |
| Molecular Weight | 309.29 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 4-Nitro-N-(4-phenylpyridin-2-yl)-1H-pyrazole-5-carboxamide |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
References
Lodoe Lama, et al Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression, Nature Communications 10:2261 (2019)