Pathway Inhibitors

J014 View larger

J014

AOB13366

CAS: N/A

Chemical Name: 4-Nitro-N-(4-phenylpyridin-2-yl)-1H-pyrazole-5-carboxamide

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$27.50

$27.50 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $12.38 Total: $1,237.50
150 $14.30 Total: $715.00
125 $16.78 Total: $419.38
110 $19.80 Total: $198.00
15 $23.38 Total: $116.88

Data sheet

Molecular FormulaC15H11N5O3
Molecular Weight309.29
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical Name4-Nitro-N-(4-phenylpyridin-2-yl)-1H-pyrazole-5-carboxamide
ReferencesLodoe Lama, et al Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression, Nature Communications 10:2261 (2019)

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Novel cGAS-specific inhibitor for repression of dsDNA-triggered interferon expression ( IC50 of 100 nM and 60.0 nM for h-cGAS and m-cGAS, respectively)


























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