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View larger AOB33844
CAS: 777857-56-4
Chemical Name: Scaff-10-8; 3-(3-(4-Methoxyphenyl)-5-methyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid
189 Items
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $67.15 | Total: $335.75 |
| 1 | 10 | $56.88 | Total: $568.80 |
| 1 | 25 | $48.19 | Total: $1,204.75 |
| 1 | 50 | $41.08 | Total: $2,054.00 |
| 1 | 100 | $35.55 | Total: $3,555.00 |
| Molecular Formula | C22H18O6 |
| Molecular Weight | 378.38 |
| CAS Numbers | 777857-56-4 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | Scaff10-8; Scaff10 8; Scaff108; Scaff-10-8; Scaff 10 8; |
| IUPAC/Chemical Name | 3-(3-(4-Methoxyphenyl)-5-methyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid |
| InChl Key | NDSJTCLAYRYLOX-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C22H18O6/c1-12-15(7-8-21(23)24)22(25)28-20-10-19-17(9-16(12)20)18(11-27-19)13-3-5-14(26-2)6-4-13/h3-6,9-11H,7-8H2,1-2H3,(H,23,24) |
| SMILES Code | O=C(O)CCC1=C(C)C2=CC3=C(OC=C3C4=CC=C(OC)C=C4)C=C2OC1=O |
| References | 1) Schrade K, Tröger J, Eldahshan A, Zühlke K, Abdul Azeez KR, Elkins JM, Neuenschwander M, Oder A, Elkewedi M, Jaksch S, Andrae K, Li J, Fernandes J, Müller PM, Grunwald S, Marino SF, Vukićević T, Eichhorst J, Wiesner B, Weber M, Kapiloff M, Rocks O, Daumke O, Wieland T, Knapp S, von Kries JP, Klussmann E. An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells. PLoS One. 2018 Jan 26;13(1):e0191423. doi: 10.1371/journal.pone.0191423. eCollection 2018. PubMed PMID: 29373579; PubMed Central PMCID: PMC5786306. |
Novel AKAP-Lbc-RhoA interaction inhibitor, promoting the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells