Pathway Inhibitors

Scaff10-8 View larger

Scaff10-8

AOB33844

CAS: 777857-56-4

 

Chemical Name: Scaff-10-8; 3-(3-(4-Methoxyphenyl)-5-methyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid

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$79.00

$79.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $35.55 Total: $3,555.00
150 $41.08 Total: $2,054.00
125 $48.19 Total: $1,204.75
110 $56.88 Total: $568.80
15 $67.15 Total: $335.75

Data sheet

Molecular FormulaC22H18O6
Molecular Weight378.38
CAS Numbers777857-56-4
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymScaff10-8; Scaff10 8; Scaff108; Scaff-10-8; Scaff 10 8;
IUPAC/Chemical Name3-(3-(4-Methoxyphenyl)-5-methyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid
InChl KeyNDSJTCLAYRYLOX-UHFFFAOYSA-N
InChl CodeInChI=1S/C22H18O6/c1-12-15(7-8-21(23)24)22(25)28-20-10-19-17(9-16(12)20)18(11-27-19)13-3-5-14(26-2)6-4-13/h3-6,9-11H,7-8H2,1-2H3,(H,23,24)
SMILES CodeO=C(O)CCC1=C(C)C2=CC3=C(OC=C3C4=CC=C(OC)C=C4)C=C2OC1=O
References1) Schrade K, Tröger J, Eldahshan A, Zühlke K, Abdul Azeez KR, Elkins JM, Neuenschwander M, Oder A, Elkewedi M, Jaksch S, Andrae K, Li J, Fernandes J, Müller PM, Grunwald S, Marino SF, Vukićević T, Eichhorst J, Wiesner B, Weber M, Kapiloff M, Rocks O, Daumke O, Wieland T, Knapp S, von Kries JP, Klussmann E. An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells. PLoS One. 2018 Jan 26;13(1):e0191423. doi: 10.1371/journal.pone.0191423. eCollection 2018. PubMed PMID: 29373579; PubMed Central PMCID: PMC5786306.

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Novel AKAP-Lbc-RhoA interaction inhibitor, promoting the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells