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Scaff10-8
AOB33844
CAS: 777857-56-4
Chemical Name: Scaff-10-8; 3-(3-(4-Methoxyphenyl)-5-methyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid
189 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $67.15 | Total: $335.75 |
| 1 | 10 | $56.88 | Total: $568.80 |
| 1 | 25 | $48.19 | Total: $1,204.75 |
| 1 | 50 | $41.08 | Total: $2,054.00 |
| 1 | 100 | $35.55 | Total: $3,555.00 |
Overview
Novel AKAP-Lbc-RhoA interaction inhibitor, promoting the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells
Chemical Properties
| Molecular Formula | C22H18O6 |
| Molecular Weight | 378.38 |
| CAS Numbers | 777857-56-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 3-(3-(4-Methoxyphenyl)-5-methyl-7-oxo-7H-furo[3,2-g]chromen-6-yl)propanoic acid |
| InChl Key | NDSJTCLAYRYLOX-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C22H18O6/c1-12-15(7-8-21(23)24)22(25)28-20-10-19-17(9-16(12)20)18(11-27-19)13-3-5-14(26-2)6-4-13/h3-6,9-11H,7-8H2,1-2H3,(H,23,24) |
| SMILES Code | O=C(O)CCC1=C(C)C2=CC3=C(OC=C3C4=CC=C(OC)C=C4)C=C2OC1=O |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
Scaff10-8; Scaff10 8; Scaff108; Scaff-10-8; Scaff 10 8;
References
1) Schrade K, Tröger J, Eldahshan A, Zühlke K, Abdul Azeez KR, Elkins JM, Neuenschwander M, Oder A, Elkewedi M, Jaksch S, Andrae K, Li J, Fernandes J, Müller PM, Grunwald S, Marino SF, Vukićević T, Eichhorst J, Wiesner B, Weber M, Kapiloff M, Rocks O, Daumke O, Wieland T, Knapp S, von Kries JP, Klussmann E. An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells. PLoS One. 2018 Jan 26;13(1):e0191423. doi: 10.1371/journal.pone.0191423. eCollection 2018. PubMed PMID: 29373579; PubMed Central PMCID: PMC5786306.