Pathway Inhibitors

SRI-37330 hydrochloride View larger

SRI-37330 hydrochloride

AOB14676

CAS: 2322245-49-6

 

Chemical Name: N-[[1-[6-(Trifluoromethyl)quinazolin-4-yl]piperidin-3-yl]methyl]methanesulfonamide;hydrochloride

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$31.00

$31.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $13.95 Total: $1,395.00
150 $16.12 Total: $806.00
125 $18.91 Total: $472.75
110 $22.32 Total: $223.20
15 $26.35 Total: $131.75

Data sheet

Molecular FormulaC16H20ClF3N4O2S
Molecular Weight424.87
CAS Numbers2322245-49-6
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymSRI-37330 hydrochloride; SRI37330 hydrochloride; SRI 37330 hydrochloride; SRI-37330 HCl; SRI37330 HCl; SRI 37330 HCl;
IUPAC/Chemical NameN-((1-(6-(trifluoromethyl)quinazolin-4-yl)piperidin-3-yl)methyl)methanesulfonamide hydrochloride
InChl KeySIWGSSRKYJTJTF-UHFFFAOYSA-N
InChl CodeInChI=1S/C16H19F3N4O2S.ClH/c1-26(24,25)22-8-11-3-2-6-23(9-11)15-13-7-12(16(17,18)19)4-5-14(13)20-10-21-15;/h4-5,7,10-11,22H,2-3,6,8-9H2,1H3;1H
SMILES CodeCS(=O)(NCC1CN(C2=C3C=C(C(F)(F)F)C=CC3=NC=N2)CCC1)=O.[H]Cl
References1) Thielen LA, et al.. Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action. Cell Metab. 2020 Sep 1;32(3):353-365.e8. doi: 10.1016/j.cmet.2020.07.002. Epub 2020 Jul 28. PMID: 32726606; PMCID: PMC7501995.

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Novel inhibitor of TXNIP expression, decreasing glucagon secretion and action and blocking hepatic glucose output, reversing obesity- and STZ-induced diabetes and hepatic steatosis

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