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BT44
AOB11052
CAS: 924759-42-2
Chemical Name: (4-(5-((3,4-Dihydroisoquinolin-2(1H)-yl)sulfonyl)-2-methoxyphenyl)piperazin-1-yl)(4-fluoro-2-(trifluoromethyl)phenyl)methanone
7000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $109.65 | Total: $548.25 |
| 1 | 10 | $92.88 | Total: $928.80 |
| 1 | 25 | $78.69 | Total: $1,967.25 |
| 1 | 50 | $67.08 | Total: $3,354.00 |
| 1 | 100 | $58.05 | Total: $5,805.00 |
Overview
Novel RET agonist for the treatment of experimental neuropathies
Chemical Properties
| Molecular Formula | C28H27F4N3O4S |
| Molecular Weight | 577.595 |
| CAS Numbers | 924759-42-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (4-(5-((3,4-Dihydroisoquinolin-2(1H)-yl)sulfonyl)-2-methoxyphenyl)piperazin-1-yl)(4-fluoro-2-(trifluoromethyl)phenyl)methanone |
| InChl Key | MFQBJWVTKPJNEP-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C28H27F4N3O4S/c1-39-26-9-7-22(40(37,38)35-11-10-19-4-2-3-5-20(19)18-35)17-25(26)33-12-14-34(15-13-33)27(36)23-8-6-21(29)16-24(23)28(30,31)32/h2-9,16-17H,10-15,18H2,1H3 |
| SMILES Code | O=C(N1CCN(C2=CC(S(=O)(N3CC4=C(C=CC=C4)CC3)=O)=CC=C2OC)CC1)C5=CC=C(F)C=C5C(F)(F)F |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
BT44; BT-44; BT 44
References
1) Sverchinsky DV, et al., Etoposide-Induced Apoptosis in Cancer Cells Can Be Reinforced by an Uncoupled Link between Hsp70 and Caspase-3. Int J Mol Sci. 2018 Aug 25;19(9):2519. doi: 10.3390/ijms19092519. PMID: 30149619; PMCID: PMC6163214.
2) Viisanen H, et al., Novel RET agonist for the treatment of experimental neuropathies. Mol Pain. 2020 Jan- Dec;16:1744806920950866. doi: 10.1177/1744806920950866. PMID: 32811276.