Potassium Channel

Glybenclamide Potassium Salt View larger

Glybenclamide Potassium Salt Bulk

AOB1218B

CAS No: 5169-35-5

 

Chemical Name: 5-​Chloro-​N-​[4-​(cyclohexylureidosulfonyl)​phenethyl]​-​2-​methoxybenzamide Potassium, Glyburide Potassium, N-p-​[2-​(5-​Chloro-​2-​methoxybenzamido)​ethyl]​benzenesulfonyl-​N′-cyclohexylurea Potassium

More details

Molarity Calculation Cart®

HOW TO ORDER

$58.00

$58.00 per 5 g

Data sheet

Molecular FormulaC23H27ClKN3O5S
Molecular Weight532.09
CAS Numbers52169-36-5
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO and Water
Purity98% by HPLC
IUPAC/Chemical NameGlibenclamide potassium; 5-Chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)-phenyl]ethyl]-2-methoxybenzamide potassium salt
InChl KeyKAJMFLAYIQKSQT-UHFFFAOYSA-N
InChl CodeInChI=1S/C23H28ClN3O5S.K/c1-32-21-12-9-17(24)15-20(21)22(28)25-14-13-16-7-10-19(11-8-16)33(30,31)27-23(29)26-18-5-3-2-4-6-18;/h7-12,15,18H,2-6,13-14H2,1H3,(H,25,28)(H2,26,27,29);/q;+1
SMILES CodeCOC1=C(C(NCCC2=CC=C(S(NC(NC3CCCCC3)=O)(=O)=O)C=C2)=O)C=C(Cl)C=C1.[K+]
References1) Coghlan, M.J., Carroll, W.A., and Gopalakrishnan, M. Recent developments in the biology and medicinal chemistry of potassium channel modulators: Update from a decade of progress. J. Med. Chem. 44(11), 1627-1653 (2001).

More info

Water soluble glyburide, inhibitor of the sulfonylurea receptor 1 (SUR1), regulating subunit of the ATP-sensitive potassium channels (KATP) in pancreatic beta cells