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F5446

Cat No: AOB17639

Condition

CAS: 2304465-89-0

Chemical Name: 1-Benzyl 7-methyl 6-((4-chlorophenyl)sulfonyl)-4,5-dioxo-3,4,5,6-tetrahydropyrrolo[3,2-e]indole-1,7-dicarboxylate

AOBIOUS launched this product in 2020

CITATIONS - Publications That Use AOBIOUS Product

1) Proc Natl Acad Sci U S A. 2022 May 24; 119(21)

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Quantity Discount Table - Order More To Get More Price Discount

Quantity	mg	Unit Price ($/mg or $/Unit)	Final Price
1	100	$116.55	Total: $11,655.00
1	50	$134.68	Total: $6,734.00
1	25	$157.99	Total: $3,949.75
1	10	$186.48	Total: $1,864.80
1	5	$220.15	Total: $1,100.75

Data sheet

Molecular Formula	C26H17ClN2O8S
Molecular Weight	552.94
CAS Numbers	2304465-89-0
Storage Condition	0°C (short term), -20°C (long term), desiccated
Solubility	DMSO
Purity	98% by HPLC
Synonym	F5446; F 5446; F-5446
IUPAC/Chemical Name	1-Benzyl 7-methyl 6-((4-chlorophenyl)sulfonyl)-4,5-dioxo-3,4,5,6-tetrahydropyrrolo[3,2-e]indole-1,7-dicarboxylate
InChl Key	MLPQCOLPRPRADV-UHFFFAOYSA-N
InChl Code	InChI=1S/C26H17ClN2O8S/c1-36-26(33)19-11-17-20-18(25(32)37-13-14-5-3-2-4-6-14)12-28-21(20)23(30)24(31)22(17)29(19)38(34,35)16-9-7-15(27)8-10-16/h2-12,28H,13H2,1H3
SMILES Code	O=C(C1=CNC2=C1C3=C(N(S(=O)(C4=CC=C(Cl)C=C4)=O)C(C(OC)=O)=C3)C(C2=O)=O)OCC5=CC=CC=C5
References	1) Lu C, et al. SUV39H1 regulates human colon carcinoma apoptosis and cell cycle to promote tumor growth. Cancer Lett. 2020 Apr 28;476:87-96. doi: 10.1016/j.canlet.2020.02.004. Epub 2020 Feb 12. PMID: 32061753; PMCID: PMC7138631. 2) Lu C, et al. SUV39H1 Represses the Expression of Cytotoxic T-Lymphocyte Effector Genes to Promote Colon Tumor Immune Evasion. Cancer Immunol Res. 2019 Mar;7(3):414-427. doi: 10.1158/2326-6066.CIR-18-0126. Epub 2019 Jan 4. PMID: 30610059; PMCID: PMC6397681.