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Tideglusib
AOB5562
CAS No:865854-05-3
Chemical Name: NP-12; NP031112; 4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione
Bulk quantity : check CFN60383
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $2.25 | Total: $225.00 |
| 1 | 50 | $2.60 | Total: $130.00 |
| 1 | 25 | $3.05 | Total: $76.25 |
| 1 | 10 | $3.60 | Total: $36.00 |
| 1 | 5 | $4.25 | Total: $21.25 |
Data sheet
| Molecular Formula | C19H14N2O2S |
| Molecular Weight | 334.39 |
| CAS Numbers | 865854-05-3 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | NP031112; NP 031112; NP-031112; Tideglusib. |
| IUPAC/Chemical Name | 2-(1-naphthalenyl)-4-(phenylmethyl)-1,2,4-thiadiazolidine-3,5-dione |
| InChl Key | PMJIHLSCWIDGMD-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C19H14N2O2S/c22-18-20(13-14-7-2-1-3-8-14)19(23)24-21(18)17-12-6-10-15-9-4-5-11-16(15)17/h1-12H,13H2 |
| SMILES Code | O=C(N1CC2=CC=CC=C2)N(C3=C4C=CC=CC4=CC=C3)SC1=O |
| References | 1) Koros C, Stamelou M. Interventions in progressive supranuclear palsy. Parkinsonism Relat Disord. 2015 Sep 25. pii: S1353-8020(15)00424-1. doi: 10.1016/j.parkreldis.2015.09.033. [Epub ahead of print] PubMed PMID: 26459661. 2) Sun A, Li C, Chen R, Huang Y, Chen Q, Cui X, Liu H, Thrasher JB, Li B. GSK-3β controls autophagy by modulating LKB1-AMPK pathway in prostate cancer cells. Prostate. 2015 Oct 6. doi: 10.1002/pros.23106. [Epub ahead of print] PubMed PMID: 26440826. |
More info
Potent non ATP-competitive inhibitor of glycogen synthase kinase-3 (GSK3)