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JPM-OET
AOB5857
CAS No: 262381-84-0
Chemical Name: (2S,3S)-3-[[[(1S)-1-[[[2-(4-Hydroxyphenyl)ethyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-2-oxiranecarboxylic acid ethyl ester
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $16.20 | Total: $1,620.00 |
| 1 | 50 | $18.72 | Total: $936.00 |
| 1 | 25 | $21.96 | Total: $549.00 |
| 1 | 10 | $25.92 | Total: $259.20 |
| 1 | 5 | $30.60 | Total: $153.00 |
Data sheet
| Molecular Formula | C20H28N2O6 |
| Molecular Weight | 392.45 |
| CAS Numbers | 262381-84-0 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | JPM-OEt; JPM OEt; JPMOEt; JPM-565 Ethyl ester |
| IUPAC/Chemical Name | ethyl (2S,3S)-3-(((S)-1-((4-hydroxyphenethyl)amino)-4-methyl-1-oxopentan-2-yl)carbamoyl)oxirane-2-carboxylate |
| InChl Key | VRFYYTLIPKHELT-ULQDDVLXSA-N |
| InChl Code | InChI=1S/C20H28N2O6/c1-4-27-20(26)17-16(28-17)19(25)22-15(11-12(2)3)18(24)21-10-9-13-5-7-14(23)8-6-13/h5-8,12,15-17,23H,4,9-11H2,1-3H3,(H,21,24)(H,22,25)/t15-,16-,17-/m0/s1 |
| SMILES Code | O=C([C@H]1O[C@@H]1C(N[C@H](C(NCCC2=CC=C(O)C=C2)=O)CC(C)C)=O)OCC |
| References | 1) Withana NP, et al., inhibition limits bone metastasis in breast cancer. Cancer Res. 2012 Mar 1;72(5):1199-209. 2) Elie BT, et al.,Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model. Biochimie. 2010 Nov;92(11):1618-24. |
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Broad spectrum cysteine cathepsin inhibitor