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SW033291 Bulk
AOB5231
CAS No: 459147-39-8
Chemical Name:2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine
4000 Items
Overview
Novel inhibitor of 15-prostaglandin dehydrogenase (15-PGDH), triggering tissue regeneration and healing of damaged tissues
Chemical Properties
| Molecular Formula | C21H20N2OS3 |
| Molecular Weight | 412.59 |
| CAS Numbers | 459147-39-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine |
| InChl Key | LCYAYKSMOVLVRL-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C21H20N2OS3/c1-2-3-12-27(24)21-19(22)18-15(14-8-5-4-6-9-14)13-16(23-20(18)26-21)17-10-7-11-25-17/h4-11,13H,2-3,12,22H2,1H3 |
| SMILES Code | NC1=C(S(CCCC)=O)SC2=NC(C3=CC=CS3)=CC(C4=CC=CC=C4)=C21 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
SW033291; SW 033291; SW 033291.
References
1) Zhang Y, Desai A, Yang SY, Bae KB, Antczak MI, Fink SP, Tiwari S, Willis JE, Williams NS, Dawson DM, Wald D, Chen WD, Wang Z, Kasturi L, Larusch GA, He L, Cominelli F, Di Martino L, Djuric Z, Milne GL, Chance M, Sanabria J, Dealwis C, Mikkola D, Naidoo J, Wei S, Tai HH, Gerson SL, Ready JM, Posner B, Willson JK, Markowitz SD. TISSUE REGENERATION. Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration. Science. 2015 Jun 12;348(6240):aaa2340. doi: 10.1126/science.aaa2340. PubMed PMID: 26068857; PubMed Central PMCID: PMC4481126.