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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $360.40 | Total: $1,802.00 |
| 1 | 10 | $305.28 | Total: $3,052.80 |
| 1 | 25 | $258.64 | Total: $6,466.00 |
| 1 | 50 | $220.48 | Total: $11,024.00 |
| 1 | 100 | $190.80 | Total: $19,080.00 |
Overview
Tri-GalNAc-DBCO is a PIP-GalNAc coupling compound that binds ASGPR to drive protein down-regulation and target compounds for protein degradation via copper-free strain-promoted azide-alkyne cycloaddition coupled to azide on a non-specifically labeled antibody.
Chemical Properties
| Molecular Formula | C82H127N11O29 |
| Molecular Weight | 1730.94 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(=O)N[C@H]1C(OCCCCC(=O)NCCCCNC(=O)CCOCC(COCCC(=O)NCCCNC(=O)CCCCOC2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2NC(C)=O)(COCCC(=O)NCCCNC(=O)CCCCO[C@@H]2O[C@H](O)[C@H](O)[C@H](O)[C@H]2NC(C)=O)NC(=O)CCCCC(=O)N2Cc3ccccc3C#Cc3ccccc32)O[C@H](CO)[C@H](O)[C@@H]1O |
Storage and Handling
0C Short Term, -20C Long Term
References
Green Ahn, et al. LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation. Nat Chem Biol. 2021 Sep;17[9] 937-946.