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View larger I-191
AOB33679
CAS No: 1690172-25-8
Chemical Name: I191; 4-(8-(tert-Butyl)-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl)-3,3-dimethylpiperazin-2-one
AOBIOUS launched this product in 2018
CITATIONS - Publications That Use AOBIOUS Product
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $21.25 | Total: $106.25 |
| 1 | 10 | $18.00 | Total: $180.00 |
| 1 | 25 | $15.25 | Total: $381.25 |
| 1 | 50 | $13.00 | Total: $650.00 |
| 1 | 100 | $11.25 | Total: $1,125.00 |
Data sheet
| Molecular Formula | C23H26FN5O2 |
| Molecular Weight | 423.49 |
| CAS Numbers | 1690172-25-8 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | I-191; I191; I 191; MDK-2258; MDK 2258; MDK2258 |
| IUPAC/Chemical Name | 4-(8-(tert-Butyl)-6-(4-fluorophenyl)imidazo[1,2-b]pyridazine-2-carbonyl)-3,3-dimethylpiperazin-2-one |
| InChl Key | DTASTQAQBOZSRR-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C23H26FN5O2/c1-22(2,3)16-12-17(14-6-8-15(24)9-7-14)27-29-13-18(26-19(16)29)20(30)28-11-10-25-21(31)23(28,4)5/h6-9,12-13H,10-11H2,1-5H3,(H,25,31) |
| SMILES Code | O=C1NCCN(C(C2=CN3N=C(C4=CC=C(F)C=C4)C=C(C(C)(C)C)C3=N2)=O)C1(C)C |
| References | Jiang Y, Yau MK, Lim J, Wu KC, Xu W, Suen JY, Fairlie DP. A Potent Antagonist of Protease-Activated Receptor 2 That Inhibits Multiple Signaling Functions in Human Cancer Cells. J Pharmacol Exp Ther. 2018 Feb;364(2):246-257. doi: 10.1124/jpet.117.245027. Epub 2017 Dec 20. PubMed PMID: 29263243 |
More info
Potent antagonist of protease-activated receptor 2 (PAR2), inhibiting multiple signaling functions in human cancer cells
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