Protein Inhibitors

EMBL View larger

EMBL

AOB36485

CAS: 445222-91-3

Chemical Name: CID-704946; 2-Amino-1'-methyl-2',5-dioxospiro[7,8-dihydro-6H-chromene-4,3'-indole]-3-carbonitrile

More details

Molarity Calculation Cart®

HOW TO ORDER

$39.00

$39.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $17.55 Total: $1,755.00
150 $20.28 Total: $1,014.00
125 $23.79 Total: $594.75
110 $28.08 Total: $280.80
15 $33.15 Total: $165.75

Data sheet

Molecular FormulaC18H15N3O3
Molecular Weight321.34
CAS Numbers445222-91-3
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymCID-704946; MuRF1-IN-1
IUPAC/Chemical Name(4R)-2-Amino-1'-methyl-2',5-dioxospiro[7,8-dihydro-6H-chromene-4,3'-indole]-3-carbonitrile
InChl KeyVXTHFLXWLSPJSP-GOSISDBHSA-N
InChl Code InChI=1S/C18H15N3O3/c1-21-12-6-3-2-5-10(12)18(17(21)23)11(9-19)16(20)24-14-8-4-7-13(22)15(14)18/h2-3,5-6H,4,7-8,20H2,1H3/t18-/m1/s1
SMILES CodeN#CC1=C(N)OC2=C(C(CCC2)=O)[C@]13C(N(C)C4=C3C=CC=C4)=O
References1) Bowen TS, Adams V, Werner S, et al. Small-molecule inhibition of MuRF1 attenuates skeletal muscle atrophy and dysfunction in cardiac cachexia. J Cachexia Sarcopenia Muscle. 2017 Dec;8(6):939-953.

More info

Novel inhibitor of MuRF1, attenuating skeletal muscle atrophy and dysfunction in cardiac cachexia









Customers who bought this product also bought: