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CPUY192018 disodium
AOB8416
CAS No: 1567836-15-0 (Free Acid)
Chemical Name: 1,4-Bis[Carboxymethyl-(4-methoxy-benzenesulfonyl)-amino]-naphthalene disodium
AOBIOUS launched this product as acid form in 2016
CITATIONS - Publications That Use AOBIOUS Product
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $20.25 | Total: $2,025.00 |
| 1 | 50 | $23.40 | Total: $1,170.00 |
| 1 | 25 | $27.45 | Total: $686.25 |
| 1 | 10 | $32.40 | Total: $324.00 |
| 1 | 5 | $38.25 | Total: $191.25 |
Data sheet
| Molecular Formula | C28H24N2Na2O10S2 |
| Molecular Weight | 658.6 |
| CAS Numbers | 1567836-15-0 (Free Acid) |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | CPUY192018 Disodium; CPUY192018-disodium; CPUY192018disodium; CPUY192018 Na2; CPUY192018; CPUY-192018; CPUY 192018 |
| IUPAC/Chemical Name | 1,4-Bis[Carboxymethyl-(4-methoxy-benzenesulfonyl)-amino]-naphthalene Disodium salt |
| InChl Key | NYLWEEROSDOHIC-UHFFFAOYSA-L |
| InChl Code | InChI=1S/C28H26N2O10S2.2Na/c1-39-19-7-11-21(12-8-19)41(35,36)29(17-27(31)32)25-15-16-26(24-6-4-3-5-23(24)25)30(18-28(33)34)42(37,38)22-13-9-20(40-2)10-14-22;;/h3-16H,17-18H2,1-2H3,(H,31,32)(H,33,34);;/q;2*+1/p-2 |
| SMILES Code | O=S(N(C1=C2C=CC=CC2=C(N(CC([O-])=O)S(=O)(C3=CC=C(OC)C=C3)=O)C=C1)CC([O-])=O)(C4=CC=C(OC)C=C4)=O.[Na+].[Na+] |
| References | 1) Lu MC, Ji JA, Jiang YL, Chen ZY, Yuan ZW, You QD, Jiang ZY. An inhibitor of the Keap1-Nrf2 protein-protein interaction protects NCM460 colonic cells and alleviates experimental colitis. Sci Rep. 2016 May 24;6:26585. doi: 10.1038/srep26585. PubMed PMID: 27215610; PubMed Central PMCID: PMC4877580. |
More info
Novel potent inhibitor of the Keap1-Nrf2 PPI protein-protein interaction, showing a cytoprotective effect against DSS in both NCM460 cells and mouse colon via the activation of Nrf2 signaling