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View larger Dynamin IN-2
AT64369
CAS 1345853-49-7
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $171.70 | Total: $858.50 |
| 1 | 10 | $145.44 | Total: $1,454.40 |
| 1 | 25 | $123.22 | Total: $3,080.50 |
| 1 | 50 | $105.04 | Total: $5,252.00 |
| 1 | 100 | $90.90 | Total: $9,090.00 |
Data sheet
| Molecular Formula | C22H21ClN2O |
| Molecular Weight | 364.87 |
| CAS Numbers | 1345853-49-7 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(C(CNCC1=CC=C(Cl)C=C1)O)N2C=3C(C=4C2=CC=CC4)=CC=CC3 |
| References | Cossar PJ, et al. Wiskostatin and other carbazole scaffolds as off target inhibitors of dynamin I GTPase activity and endocytosis. Eur J Med Chem. 2022 Dec 15;247 115001. |
More info
Dynamin IN-2 (compound 43) is a Wiskostatin analogue. Dynamin IN-2 is a potent dynamin inhibitor (dynamin I GTPase, IC50= 1.0 ?M). Dynamin IN-2 blocks clathrin mediated endocytosis (CME) (IC50= 9.5 ?M).