Protein Inhibitors

XX-650-23 View larger

XX-650-23

AOB31725

CAS: 117739-40-9


Chemical Name: N-(4-Cyanophenyl)-3-hydroxy-2-naphthamide

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$29.00

$29.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

Quantity (mg or Unit)Unit Price ($/mg or $/Unit)Final Price
100 $13.05 Total: $1,305.00
50 $15.08 Total: $754.00
25 $17.69 Total: $442.25
10 $20.88 Total: $208.80
5 $24.65 Total: $123.25

Data sheet

Molecular FormulaC18H12N2O2
Molecular Weight288.31
CAS Numbers117739-40-9
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
Shipping ConditionXX-650-23; XX 650 23; XX65023
SynonymN-(4-Cyanophenyl)-3-hydroxy-2-naphthamide
IUPAC/Chemical NameDRBIYQSSEMTUJQ-UHFFFAOYSA-N
InChl KeyInChI=1S/C18H12N2O2/c19-11-12-5-7-15(8-6-12)20-18(22)16-9-13-3-1-2-4-14(13)10-17(16)21/h1-10,21H,(H,20,22)
InChl CodeO=C(NC1=CC=C(C#N)C=C1)C2=C(O)C=C3C=CC=CC3=C2
SMILES Code1) Chae HD, Cox N, Dahl GV, Lacayo NJ, Davis KL, Capolicchio S, Smith M, Sakamoto KM. Niclosamide suppresses acute myeloid leukemia cell proliferation through inhibition of CREB-dependent signaling pathways. Oncotarget. 2017 Dec 31;9(4):4301-4317.

2) François S, Sen N, Mitton B, Xiao X, Sakamoto KM, Arvin A. Varicella-Zoster Virus Activates CREB, and Inhibition of the pCREB-p300/CBP Interaction Inhibits Viral Replication In Vitro and Skin Pathogenesis In Vivo. J Virol. 2016 Sep 12;90(19):8686-97. doi: 10.1128/JVI.00920-16. Print 2016 Oct 1. PubMed PMID: 27440893; PubMed Central PMCID: PMC5021407.

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Novel inhibitor of CREB (cAMP Response Element Binding protein)

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