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Dehydro Nifedipine View larger

Dehydro Nifedipine

AT36665

CAS 67035-22-7

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$43.00

$43.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $19.35 Total: $1,935.00
150 $22.36 Total: $1,118.00
125 $26.23 Total: $655.75
110 $30.96 Total: $309.60
15 $36.55 Total: $182.75

Data sheet

Molecular FormulaC17H16N2O6
Molecular Weight344.32
CAS Numbers67035-22-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOC(=O)c1c(C)nc(C)c(C(=O)OC)c1-c1ccccc1[N+]([O-])=O
ReferencesShimada T, et al. Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver. Proc Natl Acad Sci U S A. 1989;86[2] 462-465.

More info

Dehydro Nifedipine (BAY-b 4759) is the main metabolite of nifedipine in human plasma. Dehydro Nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 ?M. Nifedipine is a calcium channel blocker used in the treatment of hypertension and angina. Dehydronifedipine is formed when it is metabolized by cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5.